What is the safest amount of apap that can be taken in a single dose?

Answer:
1000 milligrams, up to four times daily. Do not take this much as a long-term solution, though, please see your doctor if you need further pain relief.

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In a single dose 1,000 mg. Which is like 2 Extra Strength Tylenol. Or the adult liquid apap for sore throats. This is a single dose no what you can take in a day. In a day you can take up to about 4-5,000mg a day without liver damage. Unless you do it everyday.

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